The deformation behavior and interfacial bonding properties of Cu/Al clad plates with different Cu/Al thickness-ratio by corrugated roll bonding (CRB) were investigated by shear strength test, microstructure observation of shear section and finite element simulation. The results show that increasing the Cu/Al thickness-ratio is beneficial to reduce the warpage of the Cu/Al clad plates and improve the overall bonding properties of the interface. When the Cu/Al thickness-ratio is 2:4, the Cu/Al clad plate hardly warps, and the shear strength reaches 47.24 MPa. As the Cu/Al thickness-ratio decreases, the rolling deformation zone expands and the rolling force is dispersed. Thus, the peak value of normal stress and average shear strength at the interface both decrease gradually. The shear stress generated by multiple "cross-shear" zones and the local strong normal stress formed at the interfaces during the CRB process significantly promote the plastic deformation and interface bonding of the clad plates.