The strategy of sintered closed-hole followed by reopening was proposed to prepare the microporous nickel material with high porosity through the powder metallurgy and subsequential treatments. The carbonyl nickel powder with particle size of 1 μm was used as raw material, and the effects of sintering process parameters on the pore properties and mechanical properties of microporous nickel were studied. Results show that the porosity measured by mercury injection method of microporous nickel is 53.7%, and the average pore diameter is 612.25 nm at the sintering temperature of 400 °C. After machining, the porosity measured by mercury injec-tion method is 54.0%, and the average pore diameter is 511.37 nm, which still satisfies the requirements of engineering application. The strategy provides providing a new approach for the preparation of microporous nickel and other porous metal materials.