Abstract: In bone tissue engineering, the studies on porous structures of Triply Periodic Minimal Surfaces (TPMS) are increasingly extensive. At present, the studies at home and abroad mainly focus on conventional TPMS porous structures, while the studies on deformed TPMS porous structures are few. The porous structure of deformed TPMS element has the advantage of mechanical properties in a certain direction. In this paper, a parametric design method of deformed Gyroid cell porous structure with radial and axial aperture gradients is studied. The deformed Gyroid cell porous structure samples with 60% and 75% porosity of titanium alloy are prepared by Selective Laser Melting (SLM) technology. The Finite Element Method (FEM) was used to carry out static simulation analysis on four kinds of gradient porous scaffold models and two kinds of uniform models, and the mechanical properties of the prepared titanium alloy gradient porous samples were tested, and the mechanical properties were compared and analyzed with those of the tested uniform samples. Finite element calculation results and the mechanical performance test result shows that the mechanical properties of porous structure deformation Gyroid unit decreases with porosity increased, while the porosity is the same,the radial gradient of mechanical properties of porous scaffolds is better than that of uniform porous scaffolds, more suitable for cortical bone defects of bone repair,and axial gradient of mechanical properties of porous scaffolds compared with uniform porous scaffolds weakened, more suitable for the cancellous bone.