Multi-metal composites can integrate the properties of a single component to obtain the high perforcemance and multifunctions that are difficult to be achieved by the conventional methods, which have promising application prospects. Here, it was proposed a novel approach to prepare lamellar multi-metal composites by selective laser melting and vacuum melt infiltration technology. Using Cu/316L as a model material, successfully prepared composites with delicate lamellar structure, investigated the effect of configuration variations on the properties of the composites. The results show that the properties of the lamellar composites are significantly anisotropic. With the increase of the thickness of the 316L layer, the compressive strength and the elastic modulus of the composites increase, and the electrical conductivity slightly decreases, reaching 1.96, 1.34, and 0.9 times of that of pure copper, respectively. Owing to the structural optimization (micron-scale laminations) and component selection (copper and stainless steel), the composites possess both outstanding toughness and good electrical conductivity. Moreover, the methodology provided in this work is novel and universal, providing a new approach for the design and preparation of high-performance and multifunctional composites.