Modern methods of beryllium metallurgy are based on the theory of sulfuric acid dissociation and chemical purification. Since the high solubility of sulfate produced by sulfuric acid dissociation and the overlap of the condition interval of the chemical method of separation resulted in low purity of the beryllium product and the presence of Be2+ in the separated phase, which would form a hazardous waste and reduce the yielding rate of beryllium. A transformative beryllium metallurgy theory and methodology based on the low-temperature dissociation of hydrofluoric acid and purification by exploiting the large difference of fluoride solubility is proposed. Hydrofluoric acid can quickly dissociate beryllium ore powder directly at low temperature or room temperature with a dissociation rate of more than 99%. The solubility of AlF3, FeF3, CrF3 and MgF2 is low. Coupled with the presence of common ion effect, 99.9% beryllium products can be prepared without chemical purification. For high-purity beryllium products of grade 4N or higher, high-purity beryllium can be prepared by utilizing the superior property that the pH intervals of iron, chromium, and other hydroxide precipitates are distinctly different from the pH intervals corresponding to Be(OH)2 precipitates. The new method covers a wide range of beryllium products that can be prepared by modern beryllium metallurgy.