This paper is to prepare Co-based alloy-coated metal Zr using laser melting and cladding technology, to study the difference between the high-temperature oxidation behavior of pure metal Co coatings and Co-T800 alloy coatings, as well as the wear resistance of the coatings, and also to investigate the effect of changing the laser melting process on the coatings. The oxidation weight gain of two coated Zr alloy samples at 800~1200 ℃ and the high-temperature oxidation behavior at high temperature for 1h were studied. The analysis of the results showed that the Co coating and the Co-T800 coating have better resistance to high-temperature oxidation. After oxidizing at 1000 ℃ for 1 h, the thickness of the oxide layer of the uncoated sample was 241 μm, while the thickness of the oxide layer of the Co-based coated sample was only 11.8~35.5 μm. The friction wear test showed that the depth of the abrasion mark of the coated specimen is only 1/2 of the substrate, and the hardness and wear resistance of the Zr substrate have been greatly improved. The disadvantage of Co-based coatings is the reduced performance of corrosion resistance in 3.5% NaCl solution.