Ti(C, N)-Mo₂C-Ni cermet as alternative materials was explored for use in alkaline conditions, replacing the WC-Co cemented carbides, since Co is classified as a potentially carcinogenic substance and there is potential hazard of “hard metal disease” under the exposure to cobalt dust. The changes in microstructure, corrosion rate and volumetric loss rate of the two materials were compared under electrochemical corrosion and erosion-corrosion in alkaline environment. The results demonstrates that Ti(C, N)-Mo₂C-Ni cermet undergoes passivation when exposed to electrochemical corrosion of NaOH solution, resulting in a significant increase in oxygen content on the corroded surface. The corrosion rate of cermet is approximately one order of magnitude lower than that of the cemented carbide. Under the erosion-corrosion of an alkaline sand-water mixture, both the cermet and cemented carbide experience a gradual increase in volumetric loss rate with prolonging the erosion time. During erosion, the rim phase in cermet is fragile, so cracks easily penetrate it while the core phase remains intact. The medium-grained cemented carbide commonly demonstrates transgranular fracture mode, while in the fine-grained cemented carbide, cracks tend to propagate along phase boundaries. The erosive wear and damage caused by sand particles play a predominant role in the erosion-corrosion process of alkaline sand-water mixtures. This process represents an accelerated destructive phenomenon influenced and intensified by the combined effects of corrosion and erosion. It is confirmed that using cermet as an alternative anti-wear material to cemented carbides is feasible under alkaline conditions, and even better.