The V₂O₅-MoO₃-CeO_x/TiO₂ catalyst was coated on the cordierite honeycomb ceramics by the coating method. First, the relationship between the solid content and the viscosity of the coating slurry and the choice of the organic binder in the coating slurry were studied and optimized, and the best solid content and the organic binder were screened out. Secondly, the catalytic activity of denitration in V₂O₅-MoO₃-CeO_x/TiO₂ catalyst was studied. The morphology and the crystal forms were characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD). The results showed that when the solid content was 32%, sodium carboxymethyl cellulose was used as the organic binder, the loading rate of the catalyst powder was high and the coating was firm. Compared with V₂O₅-MoO₃/TiO₂, the denitrification activity of V₂O₅-MoO₃-CeO_x/TiO₂ at 180-260 ℃ was significantly improved, and the active temperature window was widened obviously.