Microstructural evolution and mechanical properties of the election beam weldments of different thickness Ti60 titanium alloy plates were investigated in this study. Metallographic examination of as-welded Ti60 electron beam welds showed that there exhibited three zones in the EBW weldments, the fusion zone (FZ), heat affected zone (HAZ), and base metal (BM). The fusion zone was consisted of columnar grains. Effect of plate thickness on the microstructure of columnar grains is small. So the microstructure of columnar grains of different thickness plate was similar and was consisted of fine α plates and a small amount of β phase. The micro-hardness and the strength of the fusion zone was higher than the base metal. For the fusion zone, a large number of silicide precipitated in the boundary of α phase after the post weld heat treatment (PWHT) at 700℃.