Hot deformation behavior of two kinds of TC4-xFe alloys has been investigated by using a Gleeble 3800 thermal simulator at strain rates range of 1~10 s_-1 and deformation temperature range of 800~950℃ with height reduction of 60%. Based on the analysis of the stress-strain curve behaviors, two constitutive equations have been obtained, which represented as a function of deformation temperature, strain rate and flow stress.The calculated apparent activation energies are 550.77kJ/mol for TC4-0.18Fe alloy and 420.57kJ/mol for TC4-0.55Fe alloy, respectively.In order to evaluate of the flow instability areas and optimize relevant processing parameters, two processing maps were constructed at the true strain of 0.92 based on dynamic material model. The results show that the optimal processing condition with peaks in power dissipation of 0.52 and 0.47 is at the temperature of 950℃ and the strain rate of 5~10 s_-1.