Consecutive thermal cycling at 920_oC, 800_oC, 850_oC, 900_oC was performed onthe Ti-6Al-4V alloy for investigatingmicrostructure,texture evolution, tensile and rotating bending fatigue properties. After four cycles, the elongated grains in the as-received alloy disappeared due to recrystallization andthe microstructure was homogenized. Equiaxedgrains grew a little larger, from ~12mm to ~16mm, while the volumnfractionremained stable. The as-received Ti-6Al-4V alloy exhibited a transverse texture, and formed microzones parallel to the rolling direction.The rotating bending fatigue limit in the rolling direction was higher than that of the transverse direction, which was 497MPa/474MPa, respectively. The intensity of the transverse texture was weakenedafter each thermal cycle and (0001) basal texture appeared. Both the ultimateStensileSstrength and yield strength decreased for about 20MPa after four thermal cycles due to a grain coarsening. The fatigue limit of transverse/longitudinal directions decreased to441MPa/441MPa, respectively.