Using the Gleeble-1500D simulator, the high-temperature plastic deformation behavior and processing map of W-75%Cu composite were investigated at 650~950 ℃ with the strain rate of 0.01~5 s-1 and total strain of 0.7. The results show that the softening mechanism of dynamic recrystallization is a feature of high-temperature flow stress-strain curves of W-75%Cu composite, and the peak stress increases with the decrease of deformation temperature or the increase of strain rate. Based on the true stress-strain curves, the established constitutive equation represents the high-temperature flow behavior of W-75%Cu composite, and the calculated results of the flow stress are in good agreement with the experimental results of the high-temperature deformation of W-75%Cu composite. Meanwhile, the obtained processing map of Dynamic Material Modeling is used to analyze the deformation mechanism and the destabilization mechanism of W-75%Cu composite, the optimal deformation processing parameters of the deformation temperatures range and the strain rates range are 800~950 ℃ and 0.01~0.1 s-1, respectively