In order to study texture evolution and deformation mechanism during cold rolling of Zr-Sn-Nb alloys, the texture from experiments and simulations were presented and compared. Experimental texture was obtained by X-ray diffraction and simulated texture was calculated by the Taylor model with related constraints (Taylor-RC). The choice of deformation systems and their relative critical resolved shear stress (CRSS) were discussed. The results show that using a combination of slip and twinning systems with appropriate ratio of critical resolved shear stress, the simulated texture is in good agreement with the experimental one. The texture evolution of the two sheets could be interpreted by the relative activities of different slip and twinning systems, which are calculated by the Taylor-RC model.