In this study, a set of Sm-Fe-B film with different compressive stress were prepared on substrate of different prestrain by Ion Beam Spurting Deposition (IBSD). The influence of compressive stress on the magnetic anisotropy and the magnetostriction in sputter-deposited amorphous Sm-Fe-B films were investigated. Films affected by compressive stress showed in-plane anisotropy and easy axis along the direction of stress was induced in the film with the increase of compressive stress . Magnetostriction of Sm-Fe-B films affected by compressive stress was improved in low magnetic field while saturation of magnetostriction decreased slightly. At the same time, the magnetostriction rised rapidly in low field measured in a field parallel to the film plane at room temperature with the growth of compressive stress. It has also been found that the magnetic domain component which was perpendicular to the film plane increased on a small scale, though the magnetic domain or the magnetic domain component parallel to film plane still existed dominant.