F101 Ni-based alloy coating and F101 Ni-based alloy coating with 2%wt La2O3 were fabricated on TC4 titanium alloy, under proper laser cladding parameter, using F101 Ni-based fluxed alloy powder and F101 Ni-based fluxed alloy powder with 2%wt La2O3. Macro morphology, phase composition, microstructure, microhardness and friction properties of 2 kinds of the coatings were compared and analysed. The results show that: adding rare-earth La2O3 effectively improves the absorption rate of laser irradiation; more Ti-rich phases are formed and the uniformity and densification of the microstructure are improved; To some extent, the hardness and friction property of the coating are reduced due to the excessive elements diffusion from TC4 matrix into the coating, but compared with TC4, the friction coefficient of the coating is reduced (0.41 vs 0.45) and the friction property is still 2.89 times of TC4.