Bonding between tungsten and 0Cr13Al steel using a Cu/90W-5Ni-5Co powder mixtures/Ni multi-interlayer, was carried out in vacuum for 60 min at 1120 oC with a pressure of 5 MPa. The microstructures, composition distribution and fracture characteristics of the joints were studied by SEM and EDS. Joint properties were tested by shear experiments and thermal shock test. The results show that the joints comprise of tungsten/Cu-Ni-Co/tungsten heavy alloy/Ni/steel. Among them, the tungsten heavy alloy sub-layer, which is composed of uniformly distributed tungsten phase and Ni-Co matrix, is formed by solid phase sintering of 90W-5Ni-5Co powder mixtures. Sound bonding between tungsten and tungsten heavy alloy sub-layer are realized based on the transient liquid phase bonding mechanism. The average shear strength of 286 MPa has been obtained, and all the joints fracture at bonding zone of tungsten heavy alloy sub-layer and Ni sub-layer during shear testing. The results of the thermal shock tests indicate that all joints could withstand 60 cycles from 700 oC to room temperature in water.