Ti-5Al-5Mo-5V-1Fe-1Cr Ti alloy is fabricated via consumable vacuum arc-remelting furnace in this work, and then is subjected to thermo-mechanical processing and heat treatment. The microstructural characteristics and tensile properties of the heat-treated material are investigated. Primary α dispersing in β phase shows as spheroidization, near equiaxed, plate-shaped and rod-shaped after heat treatment. This is associated with boundary segregation of α grain. The material has a good combination of strength and plasticity during tensile test. However, the value of σy /σb of the material reaches 0.95. It is suggested that the grain boundary absorb dislocations during tensile test. Therefore, the dislocation strengthening increases very slowly. This is the primary reason for the material to obtain high value of σy /σb.