Ti-35Nb-7Zr-XCPP biomedical composites were prepared by a spark plasma sintering (SPS) technique. The effects of the contents of the calcium pyrophosphate (CPP) on the relative density, microstructure and mechanical properties of the composites were investigated. The results show that the composites are consisted of β-Ti phase matrix, a little residual α-Ti phase and CPP phase. The α-Ti phase of the composites increases with the increasing of the content of the CPP. Furthermore, CPP would decompose due to its excessive content in the composites. The composites present a lower compressive elastic modulus in the range of 40~62 GPa and a higher compressive strength level more than 1000 MPa, and it exhibits a better mechanical compatibility. However, the compressive elastic modulus of the composites significantly increases when the CPP is excessive, and then it would do harm to the mechanical compatibility of the composites