Centrifugal separation process was used to filtrate germanium dioxide hydrolyzed from germanium tetrachloride, and the effects of different parameters on direct?recovery rate, moisture content and chlorine content in filter cake were analyzed. The following optimized processing parameters are obtained: centrifuge filter cloth aperture 2.6 mm, the dehydration speed 1200 r/min, the filter cake thickness 80~100 mm, the single washing lotion amount 20 L, and the washing water cycle 3~5 times. The results show that the direct recovery rate of germanium dioxide can reach 99.62%, the moisture content is less than 8%, and the chlorine content is less than 0.05% in the filter cake. These samples after drying again can meet the international standard of?GeO2-06