Based on bilinear force displacement law, finite element simulation of shear force test on zirconium-titanium-steel clad plate was carried out by using cohesive zone unit of ABAQUS, then, the effect of cohesive strength and fracture energy on the damage of interface layer was studied. Also the correctness of the prediction formula of shear strength was verified. The results show that cohesive element can simulate the fracture process of clad plate interface layer and agree very well with the results of shear force tests. Shearing displacement and cohesive strength was positively correlated. With the increase of fracture energy, shearing displacement, characteristic displacement and maximum shear force increase. The fitting formula of shear strength can predict shear strength under different heat treatment.