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钱海梅,汪涛,张嘉敏,缪润杰,汤春波,汤易.植酸改性对齿科纯钛SLA表面生物活性的影响[J].稀有金属材料与工程(英文),2017,46(12):3832~3837.[qianhaimei,wangtao,zhangjiamin,miaorunjie,tangchunbo,tangyi.Effect of bioactivity on medical titanium SLA surface after modification of phytic acid[J].Rare Metal Materials and Engineering,2017,46(12):3832~3837.]
Effect of bioactivity on medical titanium SLA surface after modification of phytic acid
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Received:October 10, 2016  Revised:February 13, 2017
Key words: Qian Haimei, Wang Tao, Zhang Jiamin, Miao Runjie, Tang Chunbo, Tang Yi
Foundation item:中央高校基本科研业务费项目(NP2012303);江苏高校优势学科建设工程资助项目
Author NameAffiliationE-mail
qianhaimei Nanjing University of Aeronautics and Astronautics 335468553@qq.com 
wangtao Nanjing University of Aeronautics and Astronautics taowang@nuaa.edu.cn 
zhangjiamin Nanjing University of Aeronautics and Astronautics  
miaorunjie Nanjing University of Aeronautics and Astronautics  
tangchunbo Stomatological Hospital of Jiangsu Province  
tangyi Stomatological Hospital of Jiangsu Province  
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      In this research, the effect of phytic acid on bioactivity of the surface of SLA-titanium was studied, through modification with phytic acid and subsequent mineralization in the simulated body fluid (SBF). The microstructure, chemical properties and wettability was demonstrated, using SEM、EDS and contact angle analysis. Human bone marrow stromal cells (hBMSCs) were cultured on different surfaces to investigate the proliferation, adhesion and differentiation. The results demonstrate that the contact angle of surface modified with phytic acid is 0°, which means it is superhydrophilicity. The ability to induce apatite deposition, as well as the proliferation, adhesion differentiation of cells are improved obviously on SLA-surface, which reflect a better bioactivation treatment as a result of using phytic acid solution.