Abstract: Fretting wear test of TC4 alloy in sodium chloride solution are studied, the effects of loads on wear scars, the friction coefficient and the wear resistance are investigated under different friction counterparts. Results show that the wear mechanism attributes adhesive wear to fatigue and peeling with abrasive wear, and corrosion wear appears on the surface; The friction coefficient decreases under the sodium chloride solution and the curves keeps stable; The friction coefficient curves of Al2O3\TC4 fluctuates greatly and the wear mechanism turns fretting into reciprocating sliding under the large loads. The wear rate and wear resistance of Si3N4\TC4 is larger than that of GCr15\TC4, which means the abrasion performance of GCr15\TC4is better than that of Si3N4\TC4 and GCr15 ball performed the best wear properties under the corrosive wear. The agravity of TC4 alloy is caused by wear and the interaction of wear and corrosion in sodium chloride solution.