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王文凯,胡树兵.预钙化处理提高钽的表面生物活性[J].稀有金属材料与工程(英文),2019,48(7):2352~2357.[Wang Wenkai and Hu Shubing.Enhancement of The Bioactivity of Tantalum by Pre-Calcification[J].Rare Metal Materials and Engineering,2019,48(7):2352~2357.]
Enhancement of The Bioactivity of Tantalum by Pre-Calcification
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Received:January 26, 2018  Revised:February 13, 2018
Key words: tantalum  alkali treatment  pre-calcification  apatite
Foundation item:国家重点基础研究发展计划(973)No.2014CB046704 资助
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Wang Wenkai and Hu Shubing  
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      In order to improve the bioactivity of tantalum, NaOH solution was applied to tantalum, and the optimal concentration of alkali treatment was explored by simulating somatic fluid (SBF) soaking experiment. Alkali-treated tantalum was pre-calcified in CaCl2 solution and K2HPO4 solution, respectively. Tantalum after 0.7mol/L alkali treatment, soaked in SBF for 2 weeks, the surface can be covered with hydroxyapatite. After pre-calcification, tantalum soaked in SBF for 4 days, the surface can be covered with a layer of hydroxyapatite, indicating that pre-calcification substantially increase the bioactivity of tantalum. The mechanism is pre-calcification can make the sample surface quickly complete the nucleation of calcium and phosphorus compounds, immersed in SBF hydroxyapatite can grow rapidly.