A spray deposited 2195 Al-Li alloy ingot was extruded into plates. Some of the extruded plates were hot rolled down to the thickness of 6 mm with different finish rolling temperature, and others were cold-rolled down to the thickness of 6mm after different intermediate annealing. The surface layer of the plate with finish rolling temperature 290°C consists of coarse recrystallized grains, but the center layer cosnsits of non-recrystallized fine fibrous grains. As the finish rolling temperature is lowered to 220°C, the size of the recrystallized grain in the surface layer is decreased, but grains in the center layer are transferred to coarse elongated recystallized grains. As the intermediate annealing temperature was elevated from 330°C to 450°C, the number density of Cu-rich secondary phase particles with size larger than 1 mm increases, the recrystallized grain in the surface layer of the cold-rolled plate after solutionization coarsenes, and the center layer grain were transferred to small equi-axed recrystallized grains from coarse elongated recrystallized grains. After approporiate intermediate annealing followed by furnace cooling, the cold-rolled plate through thickness after solutionization developed into fine recrystallized grains. After a same T8 aging, the strength of the cold-rolled plates are higher than that of the hot-rolled plates, and that of the plate with a finish rolling temperature of 220°C is the lowest.