As a kind of strategic nuclear materials, uranium plays an important role in the human story. In the demand of nuclear industry, the forming and manufacturing technology of uranium and its alloy parts is also developing. This paper reviews the development of uranium material preparation and uranium parts processing technology from the view of engineering, specifically introduces the uranium alloy preparation and uranium material purification technology, and mainly describes the manufacturing methods of uranium parts from two aspects of plastic forming and casting forming. In view of the particularity of uranium products manufacturing, it points out that the technology facing future will pay more attention to safety, environmental protection and intelligence.