TiAl alloys have broad application prospects in aerospace and automobile engines, which is due to its excellent properties, such as high melting point, low density, high specific strength, good high temperature oxidation resistance, and creep resistance. Powder hot isostatic pressing can realize the integral forming of TiAl alloy parts with complex shapes, and the obtained parts have small grain size, uniform composition and excellent mechanical properties. In this paper, the principle of powder preparation by atomizing and powder hot isostatic pressing of TiAl alloys are introduced. The research states of microstructures and properties in TiAl alloys after atomization process, powder hot isostatic pressing and heat treatments are summarized. It also analyzes some problems of TiAl alloys’ powder hot isostatic pressing technology in the current, and puts forward prospects for the future development.