The influence of different cumulative rolling processes on the distribution of thermal parameters of sheet was simulated using DEFORM commercial finite element software. The dynamic globularization process of TA15 titanium alloy after thermal compression and cumulative rolling was simulated by the cellular automata. The result shows that during the accumulative roll bonding (ARB) process, the microstructure and properties of TA15 titanium alloy can be effectively improved by reducing the deformation of single pass and rolling speed as well as maintaining a certain temperature. A reasonable dynamic globularization cellular automata (CA) model was imported into Deform-3D commercial finite element simulation software and the microstructure evolution was simulated in the process of thermal compression and accumulative rolling-bonding.