A series of Ce_1-xFe_xO₂(x=0, 0.05, 0.1, 0.15, 0.2) composite oxides hollow nanospheres were successfully synthesized using the template method. Carbon spheres prepared by hydrothermal method were used as the hard template. The coating was induced by the strong oxidizing K₂FeO₄, and the electrostatic adsorption between Ce₄₊ and CS. The catalysts were characterized by means of SEM, TEM, XRD, Raman and BET. The sizes and thicknesses of hollow nanospheres were about 300 nm on average and 20~25 nm, respectively. The ratio of Fe/Ce had a significant effect on the morphology of hollow spheres. Catalytic properties were tested by catalytic oxidation of CO. Ce_0.95Fe_0.05O₂ hollow nanospheres showed an enhanced catalytic performance that the total conversion of CO was 297_oC, and also showed high stability against high temperature.