Corrosion behavior of zirconium alloy was studied by chemical immersion, electrochemical tests and physical analysis techniques. The results showed that zirconium alloy had excellent corrosion resistance in reductive HCl and low concentration H2SO4 solutions. While in high concentration H2SO4 solution, corrosion rates of zirconium alloy increased remarkably. Physical analysis techniques surface analysis results indicated that tiny grain-like ZrO2 granularly distributed on homogeneously the corrosive zirconium alloy surface. It was stable in reductive HCl and low concentration H2SO4 solutions. Thus, the corrosion resistance of zirconium alloy was strengthened. In high concentration H2SO4, for the strong oxidation of H2SO4, ZrO2 was formed continuously at the zirconium alloy/layer interface, and the thickness of this layer increased gradually. When the thickness reached certain thickness, crystal lattice parameter of the oxidation layer was not in accordance with that of the metal matrix, and inner stresses appeared, which resulted in the breakdown of the layer. And the exposed fresh zirconium alloy was oxidized by high concentration H2SO4. This process repeated regularly, which increased corrosion rate of zirconium alloy in high concentration H2SO4.