Photo-catalytic degradation of organic contaminants is currently a research focus. Recent progress in photo-catalytic degradation of organic contaminants is reviewed, and degradation of organic pollutants based on various types of photo-catalysts is also summarized. Effects of photo-catalysts under different reaction conditions, such as heat treatment temperature, pH, dosage of photo-catalysts and reactor, are compared. The conclusion will provide theoretical basis for future research and industrialization of photocatalysis technology. In the meantime, the existing problems of this technology are put forward.