Most used methods for preparation of nanometer TiO2 by using TiCl4 are reviewed, including areosol method, gas phase oxidation, gas phase combustion,liquid phase precipitation,sol-gel process, water-in-oil microemulsion and hydrothermal process. Virtues and flaws of corresponding preparation methods are also discussed. Future researching orientation of nanometer TiO2 from TiCl4 are suggested.