Powder metallurgy( PM) is an effective way to produce low-cost and high-performance titanium and titanium alloys. The as-sintered Ti-6Al-4V alloy ingots produced by hydrogenated dehydrogenation( HDH),cold isostatic pressing and vacuum pressure-less sintering have low interstitial atomic content( O < 0. 16 wt%,N < 0. 05 wt%,H < 0. 015 wt%),near-equiaxed α microstructure,better mechanical properties( R_m840 ～ 950 MPa,RP_(0.2)770 ～ 900 MPa,A12% ～ 16%). The results show that HDH process can obtain very low interstitial atomic content titanium powder. The increase of interstitial atomic concentration is mainly due to the operation,transfer and storage of powder and powder compact. Benefit from fine grain and near-net-shape characteristics of powder metallurgy titanium alloy,as-sintered ingots can be directly used to prepare final titanium alloy products without forging-cogging. Then,the near shape PM titanium can increase materials utilization rate,reduce deformation during hot working. So the as-sintered PM titanium instead of as-forged titanium can significantly reduce the cost of titanium products.