In order to accelate the application of Ti-B25 titanium alloy in ship communication system, deform-3D finite element software was used to simulate the pipe extrusion process under the deformation temperature of 900℃ and the strain rate of 0.1s-1 with the constitutive equation constructed and the process parameters optimized in the previous work. And the pipe extrusion of Ti-B25 alloy was performed to validate the results of FE simulation. The results show that the pipe blank of Φ62*Φ38 can be successfully extruded under the deformation temperature of 900℃ and the strain rate of 0.1s-1. The pipe blank has good surface quality and recrystallized microstructure. After solution aging treatment at 830℃/1h+600℃/8h, the pipe blank exhibits good stress-plastic matching. It meets the requirement of the pipes used in the shipboard antenna.