Multi-phase and multi-scale reinforced titanium matrix composites have a broad application prospects in the aerospace, and other high-tech fields due to their excellent properties such as light weight, high strength and high resistance in the elevated temperature. In the paper, the design idea, current status of advanced processing technology and engineering applications for the multi-phase and multi-scale reinforced titanium matrix composites were reviewed. The solved problems and remaining problems were pointed out, and the further research ideas were also proposed. On one hand, further optimize the existed multi-phase and multi-scale design systems and dig out the internal structure design of the titanium matrix composites in order to improve its comprehensive performance. On the other hand, the thermal processing theory and advanced thermal processing technologies should be developed to improve the processing performance in order to promote the application of lightweight high-strength titanium matrix composites in the military and other major fields.