Using hydrogenated titanium powder as raw material,large-size porous titanium plate with uniform filtration performance and width more than 400 mm was prepared by powder rolling and vacuum sintering technology through optimizing the feeding and sintering process. The experimental results show that limited feeding can achieve quantitative feeding,which can ensure the uniformity of feeding. The pressure limited sintering can effectively prevent the warpage deformation of raw material during high temperature sintering. The filtration performance of rolled porous titanium plate is good,with the density of 2. 85 g/cm~3,the maximum pore size of 37 μm,the air permeability of150 m~3/( h·k Pa·m~2),and the filtration efficiency of gas dust with partical size more then 5 μm is more than 99. 99%,which meets the demand of large-size porous titanium plate in filtration industry.