TA18 titanium alloy has become the preferred material for aerospace piping system with its excellent comprehensive performance. Although the medium strength of TA18 titanium alloy pipe has achieved mass production and industrial application, with the rapid development of China"s aviation industry, there is an urgent need for the safety and reliability of hydraulic piping system under higher working pressure. At present, there are still many problems in the mass preparation process of high-strength TA18 titanium alloy pipe. In this paper, the characteristics, development and popularization of TA18 titanium alloy will be introduced, and the effects of material composition, pipe blank preparation, rolling process and heat treatment on the quality, microstructure and properties of TA18 titanium alloy pipe will be described.