The hot compression experiment of powder forming Zr-2 alloy at 650~850℃ and strain rate 0.001~5s-1 was carried out by Gleeble-1500 thermal force simulation machine to study its hot deformation behavior. Based on the experimental data of hot compression, the strain modified Arrhenius equation was used to construct the deformation constitutive model of powder forming Zr-2 alloy. The results show that the deformation temperature has an obvious effect on the flow stress of powder forming Zr-2 alloy, and the flow stress of the material decreases greatly with the increase of deformation temperature. At the same time, the thermal deformation flow stress of powder forming Zr-2 alloy is sensitive to strain rate, that is, the deformation resistance of the material increases with the increase of strain rate, but the deformation resistance does not increase significantly at low temperature (650℃, 700℃) and high strain rate (5s-1). The constitutive equation of powder forming Zr-2 alloy based on the strain-modified Arrhenius equation has a correlation coefficient of 0.9827, which can predict the flow stress of the material accurately.